Lion’s mane contains a broad range of naturally occurring bioactive compounds, including erinacines and hericenones, known for their cognitive health benefits. These compounds found in lion’s mane can cross the protective blood-brain barrier. They stimulate the synthesis of NGF (nerve growth factor) and BDNF (brain-derived neurotrophic factor), chemicals that have potent biological activity. NGF and BDNF help to promote the growth, repair, and normal functioning of neurons, the nerve cells that are the building blocks of our brain and nervous system.